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Updated: Mar 24, 2026

Nasolacrimal Lavage as a Treatment for Ocular Surface Toxic Soup Syndrome
Published on: April 25, 2025
[Oculorrhea after facial fracture and anterior skull base fracture]
Daniel Andersson1, Gerhard Kjellén2
1Länssjukhuset i Kalmar - Öron-näs- och halskliniken Kalmar, Sweden - Kalmar, Sweden.
Abstract:
Leakage of cerebrospinal fluid (CSF) from a cranio-orbital fistula, i.e. oculorrhea, is rare after skull trauma with fewer than 30 patients reported in Western literature. Here, we for the first time report a Swedish patient. A 75-year-old male sustained a mid-facial injury due to a bicycle accident. The CT-scan showed, among other things, a fracture in the orbital roof, involving lamina cribrosa and lamina papyracea. The patient had epiphora and laboratory analysis showed CSF leakage. This diagnosis should be kept in mind when excessive tearing appears in mid-facial trauma and treatment should be considered, otherwise serious complications may occur.
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