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Updated: Mar 24, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

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Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8

Hiromi Tanji1, Umeharu Ohto1, Yuji Motoi2

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo 113-0033, Japan;

Proceedings of the National Academy of Sciences of the United States of America
|March 2, 2016
PubMed

Keywords:
Toll-like receptorX-ray crystallographyZ-loopinnate immunityproteolytic processing

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