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Related Concept Videos

Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
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Asthma-IV: Nursing Management01:30

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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Asthma-I: Introduction01:29

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

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Future treatment for asthma.

Jeremy Charriot1, Isabelle Vachier1, Laurence Halimi1

  • 1Dept of Respiratory Diseases, CHU Montpellier, Montpellier, France.

European Respiratory Review : an Official Journal of the European Respiratory Society
|March 2, 2016
PubMed
Summary
This summary is machine-generated.

Despite advancements in asthma treatments like inhaled corticosteroids and monoclonal antibodies (mAbs), uncontrolled asthma remains prevalent. Future treatments focus on personalized medicine through patient phenotyping and endotyping for targeted therapies.

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Area of Science:

  • Pulmonology
  • Pharmacology
  • Immunology

Background:

  • Asthma treatment has evolved over 40 years with inhaled corticosteroids and 20 years with monoclonal antibodies (mAbs).
  • Despite new drug classes and delivery devices, the rate of uncontrolled asthma remains persistently high.
  • Current research highlights the need for advanced patient characterization to improve treatment efficacy.

Purpose of the Study:

  • To review the evolution and future directions of asthma pharmacotherapy.
  • To explore the role of personalized medicine in managing uncontrolled asthma.
  • To discuss emerging targeted therapies, including monoclonal antibodies and novel treatment strategies.

Main Methods:

  • Literature review of inhaled corticosteroids and monoclonal antibodies in asthma management.
  • Analysis of clinical (phenotype) and biological (endotype) patient characterization tools.
  • Exploration of future therapeutic paradigms and paradigm shifts in asthma treatment.

Main Results:

  • Significant advancements in inhaled corticosteroids and monoclonal antibodies have been made.
  • Patient phenotyping and endotyping are crucial for developing personalized asthma medicine.
  • Targeted therapies represent the most promising avenue for improving outcomes in uncontrolled asthma.

Conclusions:

  • Personalized medicine, driven by detailed patient characterization, is key to overcoming challenges in asthma management.
  • The future of asthma treatment lies in targeted therapies and innovative approaches beyond current standards of care.
  • Monoclonal antibodies and novel strategies are poised to reshape the therapeutic landscape for asthma patients.