Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depression: Overview01:18

Depression: Overview

1.2K
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
1.2K
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

843
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
843
Long-term Depression01:05

Long-term Depression

33.7K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.7K
Long-term Depression01:03

Long-term Depression

3.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.5K
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

1.1K
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
1.1K
Stress and Mental Health01:30

Stress and Mental Health

1.1K
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating nutrition as a transversal competence: a curriculum mapping and implementation study in undergraduate medical education.

BMC medical education·2026
Same author

Radon balneotherapy in rheumatologic diseases: potential mechanisms and implications for cardiovascular autonomic control and inflammation.

Clinical rheumatology·2026
Same author

Do probiotics modulate dietary intake? Pilot data from a randomized controlled sub-study of the ProBioHRV clinical trial in patients with depression and healthy controls.

PloS one·2026
Same author

Validation of Noninvasive Cutaneous Carotenoid Measurements as Nutritional Biomarker Across Body Composition Groups.

Food science & nutrition·2026
Same author

A "Further-Step" Toward Considering Exercise Session Duration in Training Prescription.

Medicine and science in sports and exercise·2026
Same author

Self-touch versus muscle relaxation: Short-term benefits for physical well-being and body appreciation.

Acta psychologica·2026

Related Experiment Video

Updated: Mar 24, 2026

Burn Injury-Induced Pain and Depression-Like Behavior in Mice
07:08

Burn Injury-Induced Pain and Depression-Like Behavior in Mice

Published on: September 29, 2021

3.7K

Depression-Burnout Overlap in Physicians.

Walter Wurm1, Katrin Vogel1, Anna Holl1

  • 1Department of Psychiatry and Psychotherapeutic Medicine, Medical University of Graz, Graz, Austria.

Plos One
|March 2, 2016
PubMed
Summary
This summary is machine-generated.

Burnout and major depression symptoms significantly overlap in physicians. A multidimensional burnout assessment is more effective than the traditional three-component model for clinical evaluation.

More Related Videos

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

18.0K
A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

22.6K

Related Experiment Videos

Last Updated: Mar 24, 2026

Burn Injury-Induced Pain and Depression-Like Behavior in Mice
07:08

Burn Injury-Induced Pain and Depression-Like Behavior in Mice

Published on: September 29, 2021

3.7K
Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide
09:52

Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide

Published on: January 15, 2017

18.0K
A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

22.6K

Area of Science:

  • Occupational Health
  • Psychiatry
  • Medical Education

Background:

  • Debate exists on whether burnout is a distinct condition from depression or a syndrome with three core components.
  • The three core components of burnout are emotional exhaustion, depersonalization, and low personal accomplishment.
  • This study investigates the overlap between depression and burnout and the relevance of the three core components in a large physician sample.

Purpose of the Study:

  • To investigate the overlap in symptoms between burnout and major depression.
  • To evaluate the pertinence of the three-component burnout model in a representative sample of physicians.
  • To compare the explanatory power of different burnout component combinations for burnout severity.

Main Methods:

  • A cross-sectional study involving all Austrian physicians.
  • Utilized the Major Depression Inventory (MDI) and Hamburg Burnout Inventory (HBI).
  • Collected demographic and job-related data from 5897 participating physicians.

Main Results:

  • 10.3% of physicians had major depression; potentially 50.7% experienced burnout symptoms.
  • Increased burnout severity strongly correlated with higher odds of major depression (ORs ranging from 2.99 to 92.78).
  • A four-component burnout model (Emotional Exhaustion, Helplessness, Inner Void, Tedium) better explained burnout variance (adj.R2 = 0.92) than the three-core-component model (adj.R2 = 0.85).

Conclusions:

  • Burnout and major depression share significant symptom overlap.
  • The traditional three-dimensional burnout concept is deficient.
  • Multidimensional burnout inventories combined with depression scales are recommended for clinical assessment over solely relying on the three-component model.