Nitrogen-functionalized Isohexides in Asymmetric Induction
Marine Janvier1, Sylvie Moebs-Sanchez1, Florence Popowycz2
1Equipe Chimie Organique et Bioorganique, Institut de Chimie et Biochimie Moléculaires et Supramoléculaires, Institut National des Sciences Appliquées (INSA Lyon), Bâtiment Jules Verne, 20 Avenue Albert Einstein, F-69621 Villeurbanne Cedex, France.
Chimia
|March 3, 2016
Summary
Nitrogen-containing isohexides derived from renewable resources are synthesized and explored for their use in asymmetric catalysis. These biosourced compounds offer sustainable alternatives in chemical synthesis.
Area of Science:
- Organic Chemistry
- Catalysis
- Green Chemistry
Background:
- Biosourced isohexides have garnered significant academic and industrial interest for five decades.
- There is a growing need for sustainable chemical building blocks and catalysts.
Purpose of the Study:
- To highlight the synthesis of nitrogen-containing isohexides.
- To explore the applications of these novel isohexides in asymmetric catalysis.
Main Methods:
- Focus on synthetic strategies for incorporating nitrogen into isohexide structures.
- Investigation of catalytic performance in asymmetric reactions.
Main Results:
- Successful synthesis of various nitrogen-containing isohexides.
- Demonstration of their efficacy as catalysts in asymmetric transformations.
Conclusions:
- Nitrogen-containing isohexides represent a promising class of compounds derived from renewable resources.
- Their application in asymmetric catalysis offers a sustainable approach to chiral synthesis.
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