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The influence of espresso coffee on neurocognitive function in HIV-infected patients

M Bragança1, M Marinho1, J Marques1

  • 1a Department of Clinical Neurosciences and Mental Health, Faculty of Medicine , University of Porto , Porto , Portugal.

AIDS Care
|March 3, 2016
PubMed

Insights

Regular espresso coffee intake may improve cognitive function in people living with HIV (PLWH). This study found coffee consumption positively impacted attention, working memory, and executive functions in PLWH on antiretroviral therapy.

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Nutritional Science

Background:

  • Cognitive impairment is a concern for people living with HIV (PLWH).
  • Highly Active Antiretroviral Therapy (HAART) is standard treatment.
  • The role of lifestyle factors like coffee consumption on cognitive health in PLWH requires further investigation.

Purpose of the Study:

  • To assess the impact of coffee intake on cognitive function in PLWH.
  • To determine if coffee consumption is associated with better neuropsychological performance.

Main Methods:

  • 130 PLWH with CD4 > 200 cells/mm³ and undetectable viral load on HAART were enrolled.
  • Structured interviews collected data on coffee intake and clinical factors.
  • The HIV Neurobehavioral Research Center Battery assessed cognitive function.
  • Univariate and multivariate regression analyses were performed.

Main Results:

  • Espresso coffee consumption was significantly associated with better performance in five of eight cognitive tests.
  • Multivariate analysis indicated coffee intake positively predicted attention/working memory, executive functions, and Global Deficit Score.
  • No specific details on the type of coffee or quantity consumed were provided beyond 'espresso coffee'.

Conclusions:

  • Regular espresso coffee intake may be a favorable factor against HIV-associated cognitive deterioration.
  • Further research is needed to elucidate the mechanisms of caffeine's effect on cognitive function in PLWH.
  • Findings suggest coffee consumption could be a simple, accessible adjunct to managing cognitive health in this population.

Keywords:
HIV/AIDScaffeinecognitionneuropsychological functioningpsychiatry

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