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Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
Published on: October 31, 2025
365
[The conversion therapy for unresectable gastric cancer]
1Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]
|March 3, 2016
Summary
Conversion therapy can make unresectable gastric cancer (gastric cancer that cannot be surgically removed) treatable with surgery. This approach improves survival and quality of life for advanced gastric cancer patients.
Area of Science:
- Surgical Oncology
- Gastroenterology
- Medical Oncology
Background:
- Unresectable gastric cancer, often diagnosed at advanced stages, historically has a poor prognosis with conventional treatments.
- Traditional management primarily involves adjuvant chemotherapy, yielding limited success.
Purpose of the Study:
- To evaluate the efficacy of conversion therapy in transforming unresectable gastric cancer into a resectable state.
- To assess the impact of conversion therapy on survival and quality of life for advanced gastric cancer patients.
Main Methods:
- Systematic chemotherapy
- Radiochemotherapy
- Interventional therapy
- Hyperthermic intraperitoneal peroperative chemotherapy
Main Results:
- Conversion therapy successfully rendered initially unresectable gastric cancer cases amenable to radical D2 gastrectomy.
- Significant improvements in both survival time and quality of life were observed in patients undergoing conversion therapy.
Conclusions:
- Conversion therapy offers a promising new surgical strategy for a subset of advanced gastric cancer patients.
- This approach enhances the comprehensive treatment of unresectable gastric cancer, improving patient outcomes.
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