Related Experiment Video
Updated: Mar 24, 2026

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
Published on: December 20, 2021
Properly dividing with YAP
1Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA. gerd.pfeifer@vai.org.
Abstract:
The Hippo pathway prevents organ overgrowth and maintains tissue architecture by inhibiting the transcriptional coactivator YAP. In this issue of Science Signaling, Bui et al. find a role for YAP during cytokinesis that is independent of its transcriptional activity. This function of YAP may be important for maintaining genomic stability in dividing cells.
Related Concept Videos
Long Division of Polynomials
Synthetic Disvision of Polynomials
The Y-to-Y Circuit
Current Dividers
Determining the Plane of Cell Division
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
Determining the Plane of Cell Division

