Progression from steroid-responsive to unresponsive state in breast cancer
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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
1Hormone Biochemistry Laboratory, Imperial Cancer Research Fund, London, UK.
Abstract:
Both steroid-responsive and unresponsive cancers can be identified at first presentation. Endocrine treatment produces remission that, however, is invariably followed by relapse. The role of steroids in the genesis of the pathways involved in producing a steroid-unresponsive cancer is discussed, as are its clinical implications using data from mammary tumour cell lines.
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