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Pulmonary cryptosporidiosis in an immunocompetent host treated successfully with nitazoxanide
Harish Kumar1, Veer Bahadur Singh1, Babu Lal Meena1
1Department of Medicine, Sardar Patel (SP) Medical College, Bikaner, Rajasthan, India.
Abstract:
Cryptosporidium parvum is an intracellular spore-forming protozoa which predominantly causes intestinal diseases. It causes severe and life-threatening diarrheal diseases in immunocompromised hosts and usually self-limiting disease in immunocompetent hosts. Extra-intestinal manifestations of cryptosporidium infection are very rare. Herein, we report a case of pulmonary cryptosporidiosis in a 35-yrs-old immunocompetent host, who presented with fever, cough and breathlessness which was soon followed by diarrhea and vomiting, had lung consolidation, and treated successfully with nitazoxanide.
Insights
Pulmonary cryptosporidiosis is rare, especially in immunocompetent individuals. This case highlights a successful nitazoxanide treatment for a 35-year-old patient with lung consolidation caused by Cryptosporidium parvum.
Area of Science:
- Infectious Diseases
- Pulmonology
- Parasitology
Background:
- Cryptosporidium parvum commonly causes intestinal illness.
- Extra-intestinal manifestations are infrequent.
- Immunocompromised individuals face severe disease, while immunocompetent hosts usually experience self-limiting infections.
Purpose of the Study:
- To report a rare case of pulmonary cryptosporidiosis.
- To describe the clinical presentation and successful treatment in an immunocompetent host.
Main Methods:
- Case report of a 35-year-old immunocompetent patient.
- Clinical evaluation including symptoms (fever, cough, breathlessness, diarrhea, vomiting) and lung consolidation.
- Treatment with nitazoxanide.
Main Results:
- The patient presented with respiratory symptoms and lung consolidation.
- Symptoms progressed to include gastrointestinal distress.
- Successful treatment and recovery were achieved with nitazoxanide.
Conclusions:
- Pulmonary cryptosporidiosis can occur in immunocompetent hosts.
- Nitazoxanide is an effective treatment option.
- This case expands the understanding of Cryptosporidium parvum's extra-intestinal potential.
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