[Second line chemotherapy of carcinoma of the ovary. Current approaches]

In the present work, on the basis of the most recent knowledges, the Authors analyse and discuss the pharmacological and clinical aspects of the different types of second-line chemotherapeutical treatment for refractory ovarian cancer (standard single agent chemotherapy in high-dose schedules, new investigational anticancer agents, multidrugs chemotherapy, intraperitoneal chemotherapy).