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Published on: January 13, 2026
Isolated Tricuspid Valve Endocarditis Caused by Infection of an Implanted Central Venous Access Port Device
Shigeaki Aoyagi1, Takeshi Oda, Hayato Fukuda
1Department of Cardiovascular Surgery, St. Mary's Hospital.
Abstract:
A 70-year-old man was referred to our hospital for an intermittent high fever attributed to subcutaneous pocket infection of an implanted central venous access port device caused by methicillin-resistant staphylococcus aureus and subsequent bloodstream infection. Echocardiography revealed a large vegetation on the posterior tricuspid leaflet, annular dilatation and moderate-to-severe tricuspid regurgitation. Valve surgery was performed for persistent infection despite 8 weeks of antibiotics therapy. At operation, vegetations and torn chordae tendineae were found on the posterior tricuspid leaflet. After total resection of the posterior tricuspid leaflet, bicuspidalization valvuloplasty with prosthetic ring annuloplasty was achieved without relapse of the infection or residual regurgitation.
Insights
A central venous access port infection led to a severe tricuspid valve vegetation. Surgical repair successfully treated the infection and restored valve function.
Area of Science:
- Cardiology
- Infectious Diseases
- Cardiac Surgery
Background:
- Central venous access port infections can lead to serious complications.
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat in healthcare settings.
- Tricuspid valve involvement secondary to bloodstream infections is a critical condition.
Observation:
- A 70-year-old male presented with fever due to a pocket infection of a central venous access port, identified as MRSA.
- Bloodstream infection resulted in a large vegetation on the posterior tricuspid leaflet, causing annular dilatation and severe regurgitation.
- Despite 8 weeks of antibiotics, the infection persisted, necessitating surgical intervention.
Findings:
- Surgical exploration revealed vegetations and torn chordae tendineae on the posterior tricuspid leaflet.
- A successful bicuspidalization valvuloplasty with prosthetic ring annuloplasty was performed after resection of the affected leaflet.
- The patient experienced no relapse of infection or residual regurgitation post-surgery.
Implications:
- This case highlights the importance of early detection and management of central venous access port infections.
- Tricuspid valve repair via bicuspidalization valvuloplasty is a viable option for complex infective endocarditis.
- Aggressive surgical management can lead to favorable outcomes in persistent device-related infections affecting cardiac valves.
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Endocarditis I: Introduction
Endocarditis III: Medical Management
Endocarditis IV: Nursing Management
Endocarditis II: Clinical Features of Infective Endocarditis
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis I: Introduction

