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Updated: Aug 7, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
Upper limit of iodine in infant formulas
1Department of Pediatrics, Harbor-UCLA Medical Center, Torrance 90502.
Adequate iodine intake is crucial for thyroid hormone synthesis in infants. Current recommendations for iodine in infant formula remain appropriate, ensuring prevention of goiter and hypothyroidism.
Area of Science:
- Endocrinology
- Nutritional Science
- Pediatrics
Background:
- Iodine is essential for thyroid hormone production, preventing conditions like goiter and hypothyroidism.
- Excessive iodine intake can paradoxically inhibit thyroxine synthesis.
Purpose of the Study:
- To re-evaluate the established upper limit for iodine in infant formulas.
- To assess the safety and adequacy of current iodine intake recommendations for infants.
Main Methods:
- Review of recent scientific literature on infant iodine physiology.
- Analysis of iodine content in infant milk and formulas.
- Comparison with established and proposed iodine intake limits.
Main Results:
- Recent data suggest a safe upper limit for iodine intake in infants is 100 microg/kg body weight daily.
- The 1985 FDA recommendation of 75 microg/100 kcal for infant formulas aligns with this updated limit.
Conclusions:
- The existing upper limit for iodine in infant formulas is considered reasonable and safe for normal, term infants.
- Continued adherence to established guidelines helps ensure adequate thyroid function in infants.
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