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Related Experiment Videos

Upper limit of selenium in infant formulas.

O A Levander1

  • 1Human Nutrition Research Center, U.S. Department of Agriculture, Beltsville, MD 20705.

The Journal of Nutrition
|December 1, 1989
PubMed
Summary

Standardizing selenium levels in infant formula is crucial due to its role in preventing childhood diseases. A recommended daily intake of 10-45 micrograms of selenium is proposed for infant formulas.

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Area of Science:

  • Nutritional Science
  • Pediatric Health
  • Toxicology

Background:

  • Selenium content in infant formulas is currently uncontrolled and varies based on raw materials.
  • Selenium deficiency is linked to specific childhood diseases, necessitating standardized levels.
  • Existing data on adult selenium intake provides a basis for infant recommendations.

Purpose of the Study:

  • To propose a standardized selenium concentration for infant formulas.
  • To establish a safe and adequate daily intake range for selenium in infants.

Main Methods:

  • Extrapolation of data from adult selenium intake studies.
  • Analysis of selenium levels in human breast milk from high-selenium areas.
  • Consideration of potential toxic effects of high selenium intake.

Main Results:

  • Adult studies suggest 10 micrograms/day is sufficient for infants, while 75-160 micrograms/day may be harmful.
  • Infants in high-selenium US regions, with breast milk selenium up to 47 micrograms/day, show no reported selenosis.
  • A proposed daily intake range of 10-45 micrograms of selenium for infants.

Conclusions:

  • Standardization of selenium in infant formula is recommended.
  • A target range of 10-45 micrograms/day for infant formula selenium ensures nutritional adequacy and safety.
  • Further research may refine optimal selenium levels for infant nutrition.

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