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Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis

P Doddi1, K Gowda2, R Ramachandran1

  • 1Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Indian Journal of Nephrology
|March 4, 2016
PubMed

A 25-year-old female presented with decreased urine output, deranged renal function, thrombocytopenia, and hemolytic anemia. Kidney biopsy was consistent with thrombotic microangiopathy with acute cortical necrosis and Immunoglobulin A nephropathy (IgAN). Hemolytic anemia, thrombocytopenia and urine output improved after five sessions of plasma exchange. Renal function showed a delayed recovery and serum creatinine normalized by 3 months. This is first case of successful use of plasma exchange in hemolytic uremic syndrome with cortical necrosis associated with IgAN.

Keywords:
Hemolytic uremic syndromeImmunoglobulin A nephropathythrombotic microangiopathy

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