Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

3.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
3.4K
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

2.2K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ANGPTL2 inhibits macrophage pyroptosis and alleviates rheumatoid arthritis progression by regulating mitophagy via IGFBP5.

Cell death & disease·2026
Same author

Sirt3 Rescues Porphyromonas gingivalis-Impaired Cementogenesis via SOD2 Deacetylation.

Cell proliferation·2025
Same author

The Mdm2-p53 axis links cementocyte survival to cellular cementum volume.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2025
Same author

Chamomile Tincture and Lidocaine Hydrochloride Gel Ameliorates Periodontitis: A Preclinical Study.

Biomedicines·2024
Same author

KDM6B-Mediated HADHA Demethylation/Lactylation Regulates Cementogenesis.

Journal of dental research·2024
Same author

Smads and AP-1 activation of TGF-β signaling upregulate transcription of Osteoprotegerin in Cementoblasts to inhibit osteoclastogenesis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2024

Related Experiment Video

Updated: Mar 24, 2026

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction
06:32

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction

Published on: December 5, 2025

872

Root coverage using a coronally advanced flap with or without acellular dermal matrix: a meta-analysis.

Wei Guan1, Haiqing Liao1, Li Guo1

  • 1Department of Periodontology, The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST KLOS) & Key Laboratory for Oral Biomedical Engineering of Ministry of Education (KLOBME), School & Hospital of Stomatology, Wuhan University, Wuhan, China .

Journal of Periodontal & Implant Science
|March 4, 2016
PubMed
Summary

Coronally advanced flaps (CAFs) combined with acellular dermal matrix (ADM) show superior results for gingival recession coverage compared to CAF alone. ADM and connective tissue grafting (CTG) appear equally effective for root coverage procedures.

Keywords:
Acellular DermisGingival recessionMeta-analysis

More Related Videos

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
07:57

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

Published on: December 5, 2025

386
Engineered Vascularized Muscle Flap
08:18

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

8.8K

Related Experiment Videos

Last Updated: Mar 24, 2026

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction
06:32

Coronoid-Temporalis Pedicled Flap for Orbital Floor Defect Reconstruction

Published on: December 5, 2025

872
An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
07:57

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps

Published on: December 5, 2025

386
Engineered Vascularized Muscle Flap
08:18

Engineered Vascularized Muscle Flap

Published on: January 11, 2016

8.8K

Area of Science:

  • Periodontology
  • Regenerative Dentistry
  • Oral Surgery

Background:

  • Gingival recession presents significant esthetic challenges and can cause root sensitivity.
  • Coronally advanced flaps (CAFs) with or without acellular dermal matrix (ADM) are common root coverage techniques.

Purpose of the Study:

  • To evaluate the effectiveness of combining CAF with ADM for treating gingival recession.

Main Methods:

  • A systematic review of randomized controlled trials from PubMed, Cochrane Library, and Embase.
  • Data extraction and quality assessment by expert reviewers.
  • Analysis of clinical endpoints: recession, probing depth (PD), clinical attachment level (CAL), and keratinized tissue (KT).

Main Results:

  • Ten trials were included; six compared CAF+ADM with CAF+connective tissue grafting (CTG), and four compared CAF+ADM with CAF alone.
  • No significant difference was found between ADM and CTG.
  • CAF+ADM demonstrated statistically significant improvements in recession coverage, CAL, and KT compared to CAF alone.

Conclusions:

  • Both ADM and CTG appear equally effective for root coverage.
  • Further research is recommended to fully elucidate the clinical efficacy of ADM with CAF.