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Sertoli-Leydig cell tumor of the ovary: A diagnostic dilemma
Casandra A Liggins1, Ly T Ma2, Matthew P Schlumbrecht3
1Department of Obstetrics and Gynecology at Banner University Medical Center, Phoenix, AZ, USA.
Background:
Sertoli-Leydig cell tumors are rare sex-cord stromal tumors of the ovary that can present with a variety of histological elements, which may complicate diagnosis and treatment.
Case:
A 40-year-old female presenting with pelvic pain is found to have a large complex right adnexal mass and elevated alpha-fetoprotein. The mass was diagnosed as a Sertoli-Leydig cell tumor with heterologous elements including carcinoid and hepatoid components. She was treated with surgical resection followed by adjuvant chemotherapy and remains clear of disease.
Conclusion:
Prognostic indicators for Sertoli-Leydig cell tumors include degree and type of heterologous element differentiation. Thorough characterization of such elements is crucial for adequate diagnosis and treatment.
