Related Experiment Video
Updated: Mar 24, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Current clinical practice guidelines in atrial fibrillation: a review
José Kelvin Galvez-Olortegui1, Mayita Lizbeth Álvarez-Vargas2, Tomas Vladimir Galvez-Olortegui3
1Scientia Clinical and Epidemiological Research Institute, Trujillo, Perú; Facultad de Medicina, Universidad Nacional de Trujillo, Trujillo, Perú; G.A.C. N° 116, Centro Médico 32° Brigada de Infantería, Ejército del Perú, Trujillo, Perú; Guidelines International Network, Escocia. Address: Scientia Clinical and Epidemiological Research Institute, Manzana G, Lote 22, Urbanización Vista Hermosa, Trujillo, La Libertad, Perú.
This study evaluated clinical practice guidelines for atrial fibrillation using the AGREE II instrument. NICE and American guidelines scored highest, showing good global quality for clinical use.
Area of Science:
- Cardiology
- Clinical Practice Guidelines
- Methodology Evaluation
Background:
- Atrial fibrillation management relies on clinical practice guidelines.
- Methodological quality of these guidelines varies.
- This study is part of a series evaluating cardiology guidelines.
Purpose of the Study:
- To methodologically evaluate clinical practice guidelines for atrial fibrillation.
- To compare the quality of American, Canadian, and NICE guidelines.
Main Methods:
- Utilized the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument.
- Assessed selected clinical practice guidelines for atrial fibrillation.
- Analyzed methodology and content of selected guidelines.
Main Results:
- Guidelines scored lowest in applicability (mean 36.1%) and highest in clarity of presentation (mean 93.5%).
- Canadian guideline had the lowest score in editorial independence.
- NICE guideline achieved the highest score in applicability.
Conclusions:
- NICE and American guidelines demonstrated the best overall quality via the AGREE II instrument.
- Both NICE and American guidelines are recommended for use without modifications.
- Methodological rigor, particularly in applicability and editorial independence, remains an area for improvement in guideline development.
Related Concept Videos
Dysrhythmias VI: Management of Dysrhythmias
Peripheral Artery Disease III: Interprofessional Care
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Venous Thrombosis III: Interprofessional Care
Atherosclerosis III: Management
Rheumatic Heart Disease III: Medical Management

