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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

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[ASA - from cardiovascular to cancer prevention]

Veronika Sanin, Vanessa Pfetsch, Wolfgang Koenig

    Deutsche Medizinische Wochenschrift (1946)
    |March 4, 2016
    PubMed

    Insights

    Low-dose aspirin (ASA) effectively prevents vascular events in secondary prevention but its use in primary prevention remains debated. This review examines ASA

    Area of Science:

    • Cardiovascular Medicine
    • Oncology
    • Pharmacology

    Context:

    • Cardiovascular disease and cancer are leading global causes of death.
    • Low-dose aspirin (ASA) is established for secondary prevention of atherothrombotic events.
    • Controversy exists regarding ASA's role in primary cardiovascular prevention.

    Purpose:

    • To review evidence on low-dose ASA efficacy in primary and secondary cardiovascular prevention.
    • To discuss the potential chemopreventive benefits of ASA.

    Summary:

    • ASA significantly reduces atherothrombotic vascular complications in patients with prior myocardial infarction, peripheral arterial occlusive disease (PAOD), or stroke.
    • In secondary prevention, ASA's benefits outweigh its risks.
    • Evidence for ASA in primary prevention is still under debate, with ongoing research into its broader chemopreventive potential.

    Impact:

    • Informs clinical guidelines for aspirin use in cardiovascular disease prevention.
    • Highlights the need for further research into aspirin's dual role in cardiovascular and cancer prevention.
    • Provides a comprehensive overview for healthcare professionals and researchers in cardiology and oncology.

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