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Osteoinduction: a report on the discovery and research of unique protein growth factors mediating bone development
1Cellular Biochemistry Department, Collagen Corporation, Palo Alto, Calif.
Oral Surgery, Oral Medicine, and Oral Pathology
|October 1, 1989
Abstract:
Osteoinductive factor, a unique glycoprotein, is the latest growth factor to be discovered. When combined with transforming growth factor-beta 1 or transforming growth factor-beta 2, osteoinductive factor can stimulate the formation of endochondral bone in a collagen-ceramic composite. Preliminary laboratory studies indicate a wide potential for the use of osteoinductive products in orthopedics, oral reconstruction, and periodontal procedures.