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First High-Quality Draft Genome Sequence of Pasteurella multocida Sequence Type 128 Isolated from Infected Bone

Niloofar Kavousi1, Wilhelm Wei Han Eng1, Yin Peng Lee1

  • 1Monash University Malaysia Genomics Facility, Monash University Malaysia, Jalan Lagoon Selatan, Selangor, Malaysia School of Science, Monash University Malaysia, Jalan Lagoon Selatan, Selangor, Malaysia.

Genome Announcements
|March 5, 2016
PubMed

Insights

We sequenced the Pasteurella multocida genome from a dog bite infection. This high-quality draft genome provides crucial data for understanding this bacterium.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • Pasteurella multocida is a significant bacterial pathogen.
  • Genomic data for P. multocida, especially from clinical isolates, is limited.
  • Understanding P. multocida's genetic makeup is crucial for developing effective treatments.

Purpose of the Study:

  • To generate a high-quality draft genome sequence of a Pasteurella multocida strain.
  • To provide a valuable genomic resource for P. multocida research.
  • To aid in understanding P. multocida infections, particularly those resulting from animal bites.

Main Methods:

  • Whole-genome sequencing of Pasteurella multocida.
  • Bioinformatic analysis of the resulting sequence data.
  • Isolation of the bacterium from a clinical sample.

Main Results:

  • A high-quality draft genome sequence of Pasteurella multocida sequence type 128 was successfully generated.
  • The isolate was obtained from an infected finger bone following a domestic dog bite.
  • This represents the first genome sequence for this specific P. multocida sequence type.

Conclusions:

  • The generated draft genome is a valuable resource for the scientific community.
  • This genomic data can facilitate further research into Pasteurella multocida pathogenesis and evolution.
  • Enhanced genomic information can contribute to improved diagnostics and therapeutics for P. multocida infections.

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