First High-Quality Draft Genome Sequence of Pasteurella multocida Sequence Type 128 Isolated from Infected Bone

Area of Science:

• Microbiology
• Genomics
• Infectious Diseases

Background:

• Pasteurella multocida is a significant bacterial pathogen.
• Genomic data for P. multocida, especially from clinical isolates, is limited.
• Understanding P. multocida's genetic makeup is crucial for developing effective treatments.

Purpose of the Study:

• To generate a high-quality draft genome sequence of a Pasteurella multocida strain.
• To provide a valuable genomic resource for P. multocida research.
• To aid in understanding P. multocida infections, particularly those resulting from animal bites.

Main Methods:

• Whole-genome sequencing of Pasteurella multocida.
• Bioinformatic analysis of the resulting sequence data.
• Isolation of the bacterium from a clinical sample.

Main Results:

• A high-quality draft genome sequence of Pasteurella multocida sequence type 128 was successfully generated.
• The isolate was obtained from an infected finger bone following a domestic dog bite.
• This represents the first genome sequence for this specific P. multocida sequence type.

Conclusions:

• The generated draft genome is a valuable resource for the scientific community.
• This genomic data can facilitate further research into Pasteurella multocida pathogenesis and evolution.
• Enhanced genomic information can contribute to improved diagnostics and therapeutics for P. multocida infections.