Related Experiment Video
Updated: Mar 24, 2026

Live Cell Imaging of F-actin Dynamics via Fluorescent Speckle Microscopy FSM
Published on: August 5, 2009
Imaging Hidden Objects with Spatial Speckle Intensity Correlations over Object Position
Jason A Newman1, Qiaoen Luo1, Kevin J Webb1
1School of Electrical and Computer Engineering, Purdue University, 465 Northwestern Avenue, West Lafayette, Indiana 47907, USA.
Abstract:
We present a coherent optical method for wavelength-resolution imaging of moving objects hidden within thick randomly scattering media. Spatial speckle intensity correlations as a function of object position are shown to provide access to the spatially dependent dielectric constant of the moving object. This speckle correlation imaging method yields field-based information previously inaccessible in heavily scattering environments. Proof of concept experimental results show excellent agreement with the theory. This new imaging approach will be valuable in high resolution imaging in tissue and other scattering environments where natural motion occurs or the object position can be controlled.
More Related Videos
Related Concept Videos
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
Super-resolution Fluorescence Microscopy

