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Related Experiment Video

Updated: Mar 24, 2026

Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method

Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method

Published on: July 4, 2021

Septic cerebral venous sinus thrombosis.

Ismail A Khatri¹, Mohammad Wasay²

¹King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.

Journal of the Neurological Sciences

|March 6, 2016

Summary

Septic cerebral venous sinus thrombosis, though rare, requires high clinical suspicion for prompt diagnosis and management. Early antibiotics, imaging, and anticoagulation are crucial for preventing severe complications and death.

Keywords:

Anticoagulation Cavernous sinus thrombosis Cerebral venous thrombosis Diagnosis Management Septic

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Establishment of a Rat Model of Superior Sagittal-Sinus Occlusion via a Thread-Embolism Method

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Published on: July 4, 2021

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

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Published on: October 20, 2017

Area of Science:

Neurology
Infectious Diseases
Vascular Medicine

Background:

Septic cerebral venous sinus thrombosis (SCVTS) incidence has decreased due to antibiotics, but remains a serious condition.
Cavernous sinus thrombosis is the most common form of SCVTS.
Clinicians may lack experience with SCVTS due to its rarity.

Purpose of the Study:

To review the current understanding of SCVTS.
To summarize diagnostic and management strategies for SCVTS.
To emphasize the importance of clinical suspicion in SCVTS.

Main Methods:

Literature review of historical and current data on SCVTS.
Analysis of clinical presentations, diagnostic modalities, and treatment approaches.
Synthesis of information to guide contemporary clinical practice.

Main Results:

SCVTS presents dramatically with fever, periorbital pain/swelling, and systemic signs, often preceded by facial or sinus infections.
Rapid contralateral spread and potential for severe complications or death if untreated.
Prompt diagnosis via imaging, early broad-spectrum antibiotics, and judicious anticoagulation are key.

Conclusions:

High clinical suspicion is paramount for timely SCVTS diagnosis and management.
Multimodal treatment including antibiotics, imaging, and anticoagulation can improve outcomes.
Surgical intervention is reserved for addressing the source of infection.