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Updated: Mar 24, 2026

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
Phosphate excretion is decreased in older cardiac patients with normal kidney function: an emerging dietary risk
Alexis Jozefacki1, Christine A White1, Navid S Shobeiri2
1a Department of Medicine, Queen's University, Kingston, ON K7L 3N6, Canada.
Abstract:
Serum phosphate independently predicts cardiovascular events and mortality. Sixteen healthy adults and 9 adults with cardiovascular disease (CVD) ingested 500 mg of sodium phosphate after an over-night fast. In control subjects, the urine phosphate/creatinine ratio was significantly higher at 2 h (3.12 ± 1.02) than at baseline (1.98 ± 0.58, p < 0.001) but no change was observed in CVD patients. Decreased postprandial urinary excretion of phosphate could accelerate vascular calcification and may be an under-recognized risk factor for CVD.
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