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Risk Factors and In-Hospital Outcomes following Tracheostomy in Infants
Jan Hau Lee1, P Brian Smith2, M Bin Huey Quek3
1Children's Intensive Care Unit, KK Women's and Children's Hospital, Singapore; Duke-National University of Singapore School of Medicine, Singapore.
Insights
Tracheostomy is uncommon in hospitalized infants but carries a high mortality risk. Factors like near-term gestational age and pulmonary diagnoses increase mortality risk in these infants.
Area of Science:
- Neonatal intensive care
- Pediatric surgery
- Respiratory medicine
Background:
- Tracheostomy is a critical intervention for infants requiring prolonged mechanical ventilation.
- Understanding the epidemiology and outcomes of infant tracheostomy is essential for improving care.
- Data on tracheostomy use and associated mortality in neonatal intensive care units (NICUs) is limited.
Purpose of the Study:
- To describe the epidemiology of tracheostomy in infants within NICUs.
- To identify risk factors associated with tracheostomy in this population.
- To analyze in-hospital outcomes and mortality rates following tracheostomy.
Main Methods:
- Analysis of electronic medical records from 348 NICUs between 1997 and 2012.
- Evaluation of infant demographics, diagnoses, and pretracheostomy support.
- Assessment of trends in infant tracheostomy utilization over time.
Main Results:
- Tracheostomy was performed in 0.1% of infants, with common diagnoses including bronchopulmonary dysplasia and airway anomalies.
- In-hospital mortality after tracheostomy was 14%.
- Increased mortality was linked to near-term gestational age, small for gestational age status, pulmonary diagnoses, oxygen support, and inotropic support.
Conclusions:
- Tracheostomy is infrequently performed in hospitalized infants but is associated with significant in-hospital mortality.
- Near-term gestational age, small for gestational age status, and pulmonary diagnoses are key risk factors for mortality.
- The proportion of infants undergoing tracheostomy increased until 2005 and has since stabilized.
Objective:
To describe the epidemiology, risk factors, and in-hospital outcomes of tracheostomy in infants in the neonatal intensive care unit.
Study Design:
We analyzed electronic medical records from 348 neonatal intensive care units for the period 1997 to 2012, and evaluated the associations among infant demographics, diagnoses, and pretracheostomy cardiopulmonary support with in-hospital mortality. We also determined the trends in use of infant tracheostomy over time.
Results:
We identified 885 of 887 910 infants (0.1%) who underwent tracheostomy at a median postnatal age of 72 days (IQR, 27-119 days) and a median postmenstrual age of 42 weeks (IQR, 39-46 weeks). The most common diagnoses associated with tracheostomy were bronchopulmonary dysplasia (396 of 885; 45%), other upper airway anomalies (202 of 885; 23%), and laryngeal anomalies (115 of 885; 13%). In-hospital mortality after tracheostomy was 14% (125 of 885). On adjusted analysis, near-term gestational age (GA), small for GA status, pulmonary diagnoses, number of days of forced fraction of inspired oxygen >0.4, and inotropic support before tracheostomy were associated with increased in-hospital mortality. The proportion of infants requiring tracheostomy increased from 0.01% in 1997 to 0.1% in 2005 (P < .001), but has remained stable since.
Conclusion:
Tracheostomy is not commonly performed in hospitalized infants, but the associated mortality is high. Risk factors for increased in-hospital mortality after tracheostomy include near-term GA, small for GA status, and pulmonary diagnoses.
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