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Mental Health in Children Born Extremely Preterm Without Severe Neurodevelopmental Disabilities
Silje Katrine Elgen Fevang1, Mari Hysing2, Trond Markestad3
1Department of Clinical Science, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway; and silje.elgen@uib.no.
Insights
Extremely preterm/low birth weight children face higher risks for autism, inattention, anxiety, and OCD. These mental health challenges in children born extremely preterm/low birth weight were similar across genders.
Area of Science:
- Pediatric Health
- Neurodevelopmental Disorders
- Child Psychology
Background:
- Extremely preterm/extremely low birth weight (EP/ELBW) children are a vulnerable population.
- Understanding mental health challenges in this group is crucial for early intervention.
- Previous studies highlight potential developmental risks, but comprehensive mental health assessments are needed.
Purpose of the Study:
- To determine the prevalence and gender-specific characteristics of mental health problems in EP/ELBW children at age 11.
- To compare mental health outcomes in EP/ELBW children (without severe disabilities) to a reference group.
Main Methods:
- A national cohort of EP/ELBW children and a reference group were assessed at 11 years of age.
- Parent and teacher reports were used to evaluate symptoms of autism, ADHD, anxiety, and OCD.
- Pervasive mental health problems were defined by high percentile scores from multiple validated questionnaires.
Main Results:
- EP/ELBW children showed significantly increased risks for pervasive autism symptoms (OR 4.3), inattention (OR 8.3), anxiety (OR 2.3), and OCD (OR 2.6).
- Overall, 54% of EP/ELBW children had at least one mental health problem compared to 21% in the reference group (OR 4.5).
- No significant gender interactions were found for mental health outcomes in EP/ELBW children.
Conclusions:
- EP/ELBW children, even without severe disabilities, exhibit a higher risk for various mental health issues including autism spectrum disorder, ADHD, anxiety, and OCD.
- The observed mental health disparities between EP/ELBW children and their peers warrant targeted support and monitoring.
- Gender did not significantly influence the mental health outcomes in this cohort of EP/ELBW children.
Objective:
To describe the prevalence and gender characteristics of mental health problems in extremely preterm/extremely low birth weight (EP/ELBW) children without intellectual disabilities, blindness, deafness, or severe cerebral palsy compared with a reference group at 11 years of age.
Methods:
In a national cohort of EP/ELBW children, mental health was assessed by parental and teacher report by using the Autism Spectrum Screening Questionnaire, the Swanson, Noland, and Pelham Questionnaire IV (attention-deficit/hyperactivity disorder), the Screen for Child Anxiety Related Emotional Disorders, symptoms of obsessive-compulsive disorder (OCD), and a total difficulties score from the Strength and Difficulties Questionnaire. Pervasive rating was defined as both parent and teacher scoring the child ≥95th percentile (≥90th percentile for total difficulties score) of the reference group, which was the population-based Bergen Child Study.
Results:
Of eligible children, 216 (64%) EP/ELBW and 1882 (61%) reference children participated. EP/ELBW children were at significantly increased risk of pervasive rated symptoms of autism (odds ratio 4.3, 95% confidence interval 2.0-9.3), inattention (8.3, 4.4-15), anxiety (2.3, 1.4-3.7), OCD (2.6, 1.4-3.7), and ≥90th percentile for total difficulties score (4.9, 2.9-8.2). Reported by either parents or teachers, 54% of the EP/ELBW and 21% of the reference children had ≥1 mental health problem (odds ratio 4.5, 95% confidence interval 3.3-6.1). There were no significant interactions between EP/ELBW and gender in mental health outcomes.
Conclusions:
EP/ELBW children without severe disabilities had increased risk of symptoms of autism, inattention, anxiety, and OCD. Gender differences were comparable to the reference group.
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