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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Mechanical thrombectomy in pediatric acute ischemic stroke: Clinical outcomes and literature review
Thomas P Madaelil1, Akash P Kansagra2, DeWitte T Cross3
1Department of Neuroradiology, Mallinckrodt Institute of Radiology, USA madaelilt@mir.wustl.edu.
Insights
Mechanical thrombectomy using modern devices shows promising results for pediatric acute ischemic stroke. This treatment achieved 100% vessel recanalization and 91% favorable clinical outcomes in a recent study and literature review.
Area of Science:
- Neurology
- Interventional Neurology
- Pediatric Neurology
Background:
- Limited data exist on mechanical thrombectomy for pediatric stroke with modern devices.
- Acute ischemic stroke in children requires effective treatment strategies.
Observation:
- Two pediatric cases of acute ischemic stroke were treated with mechanical thrombectomy using modern devices.
- Both cases achieved excellent angiographic results (TICI 3).
- Both patients experienced no neurological deficits at 90 days.
Findings:
- A literature review combined with these cases showed 100% vessel recanalization (22/22).
- The aggregate rate of favorable clinical outcomes was 91% (20/22).
- Modern thrombectomy devices demonstrated high efficacy in pediatric stroke.
Implications:
- Mechanical thrombectomy with modern devices may be a safe and effective option for pediatric acute ischemic stroke.
- Further research is warranted to confirm these preliminary findings.
- This approach could improve outcomes for children experiencing ischemic stroke.
Abstract:
There are limited data on outcomes of mechanical thrombectomy for pediatric stroke using modern devices. In this study, we report two cases of pediatric acute ischemic stroke treated with mechanical thrombectomy, both with good angiographic result (TICI 3) and clinical outcome (no neurological deficits at 90 days). In addition, we conducted a literature review of all previously reported cases describing the use of modern thrombectomy devices. Including our two cases, the aggregate rate of partial or complete vessel recanalization was 100% (22/22), and the aggregate rate of favorable clinical outcome was 91% (20/22). This preliminary evidence suggests that mechanical thrombectomy with modern devices may be a safe and effective treatment option in pediatric patients with acute ischemic stroke.
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