Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

The Mauriac syndrome.

E Y Morrison, K McKenzie

The West Indian Medical Journal

|September 1, 1989

Summary

This summary is machine-generated.

This case study describes a young patient with insulin-dependent diabetes who experienced complications including liver enlargement and ketoacidosis. The symptoms resolved with improved diabetes management, but the patient later died suddenly.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Empathic Accuracy and Cognitive and Affective Empathy in Young Adults With and Without Autism Spectrum Disorder.

Journal of autism and developmental disorders·2021

Same author

A qualitative investigation of patients' understanding of carbohydrate in the clinical management of type 2 diabetes.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2015

Same author

Poor mental health in severely obese patients is not explained by the presence of comorbidities.

Clinical obesity·2014

Same author

Smartphone apps for urolithiasis.

Urolithiasis·2014

Same author

405 nm light technology for the inactivation of pathogens and its potential role for environmental disinfection and infection control.

The Journal of hospital infection·2014

Same author

A meta-analysis of ethnic differences in pathways to care at the first episode of psychosis.

Acta psychiatrica Scandinavica·2014

Same journal

Prevalence of Sickle Cell Disease among Newborns in St Vincent and the Grenadines: A Retrospective Study.

The West Indian medical journal·2024

Same journal

Emergence of Zika Virus Epidemic and the National Response in Jamaica.

The West Indian medical journal·2017

Same journal

Unravelling the Paediatric and Perinatal Zika Virus Epidemic through Population-based Research.

The West Indian medical journal·2017

Same journal

The Condition of Oral Health in Regular Users of Psychoactive Substances.

The West Indian medical journal·2017

Same journal

Polypharmacy and the Risk of Malnutrition among Independently-living Elderly Persons in Trinidad.

The West Indian medical journal·2017

Same journal

Cutaneous Chylous Bubbles and Lymphatic Pilar Reflux in a Patient with Juxta-articular Dercum's Disease: A Very Rare Case.

The West Indian medical journal·2017

See all related articles

Area of Science:

Pediatric Endocrinology
Metabolic Disorders

Background:

Presents a case of a young patient diagnosed with insulin-dependent diabetes at age 7.
Highlights the challenges in achieving stable glycemic control in pediatric diabetes.

Observation:

The patient experienced recurrent hyperglycemic ketoacidosis and developed tender hepatomegaly.
Hepatomegaly regressed upon stabilization of diabetes, but the patient exhibited growth failure below the tenth percentile.
Sudden death occurred at age 12.5, with post-mortem findings of ascites, hepatomegaly, and fatty liver changes.

Findings:

The clinical presentation, including high insulin requirements (2.3 IU/kg/day), hepatomegaly, unstable diabetes, and growth failure, strongly suggests Mauriac syndrome.
Fatty metamorphosis of the liver was noted on post-mortem examination.

Related Experiment Videos

Implications:

This case underscores the potential for severe complications in poorly controlled pediatric diabetes.
Emphasizes the importance of vigilant monitoring and management to prevent long-term sequelae like Mauriac syndrome.
Highlights the link between chronic hyperglycemia and hepatic complications in diabetic children.