Genomics of local adaptation with gene flow

Area of Science:

• Evolutionary biology
• Genomics
• Population genetics

Background:

• Gene flow is a critical evolutionary force influencing adaptation.
• Traditional theory often highlights gene flow's disruptive effects on adaptation.
• Human-induced environmental changes are altering natural gene flow levels.

Purpose of the Study:

• To review the genomics of adaptation in the context of gene flow.
• To explore selection on migration and gene flow.
• To discuss sources of adaptive variation and maintenance of local adaptation.

Main Methods:

• Synthesis of recent genomic models of adaptation.
• Discussion of genomic mechanisms driving adaptation.
• Review of empirical studies on the genomics of adaptation with gene flow.

Main Results:

• Gene flow can promote adaptation, contrary to some predictions.
• Local adaptations can persist even under high gene flow conditions.
• Genetic architecture significantly influences the origin and maintenance of adaptation.

Conclusions:

• Genomic approaches have advanced the understanding of gene flow's role in adaptation.
• Genetic architecture is fundamental for adaptation with gene flow.
• Future research should leverage genomic insights to study adaptation dynamics.