Meroterpenoid enantiomers from Ganoderma sinensis
Related Experiment Video
Updated: Mar 24, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
Published on: June 13, 2022
Wen-Wen Cao1, Qi Luo2, Yong-Xian Cheng3
1Guangdong Pharmaceutical University, Guangzhou 510006, PR China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
Abstract:
Zizhines A-F (1-6), six pairs of new meroterpenoid enantiomers and a known meroterpenoid (7) were isolated from the fruiting bodies of Ganoderma sinensis. The structures and absolute configurations of the new substances were assigned by spectroscopic and computational methods. All the compounds apart from 7 were evaluated for their inhibition on extracellular matrix component (fibronectin) generation by using TGF-β1-induced rat kidney tubular epithelial cells. Although none of them was found to be active in these cells, the present findings add new facets for the chemistry of Ganoderma.
More Related Videos
Related Concept Videos
Properties of Enantiomers and Optical Activity
Racemic Mixtures and the Resolution of Enantiomers
Prochirality
Stereoisomers
Naming Enantiomers
Molecules with Multiple Chiral Centers

