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A Randomized Controlled Trial of an Outpatient Protocol for Transitioning Children from Tube to Oral Feeding: No Need

Ann M Davis1, Kelsey Dean2, Hayat Mousa3

  • 1Department of Pediatrics, University of Kansas Medical Center, Kansas City, KS; Center for Children's Healthy Lifestyles and Nutrition, Kansas City, MO.

The Journal of Pediatrics
|March 8, 2016
PubMed

Insights

This study found that an outpatient feeding program effectively weaned children from tube to oral feeding. Amitriptyline was not essential to the protocol's success in improving feeding outcomes.

Area of Science:

  • Pediatric Gastroenterology
  • Clinical Nutrition
  • Pharmacology

Background:

  • Medically complex children often require tube feeding.
  • Weaning to oral feeding is a critical developmental milestone.
  • Outpatient multidisciplinary feeding programs aim to facilitate this transition.

Purpose of the Study:

  • To evaluate the role of amitriptyline in an outpatient feedingWeaning protocol.
  • To assess the effectiveness of a comprehensive protocol for transitioning children from tube to oral feeding.

Main Methods:

  • A randomized placebo-controlled trial involving 21 children across 4 sites.
  • A 6-month outpatient treatment protocol incorporating behavioral, oral-motor, nutrition, and medication components.
  • Comparison of outcomes between amitriptyline and placebo groups.

Main Results:

  • 73% of children successfully transitioned to oral feeding by the end of the 6-month program.
  • The transition to oral feeding led to reduced body mass index percentile and pain.
  • Improvements in quality of life were observed, with no significant cost changes.

Conclusions:

  • The interdisciplinary outpatient protocol is effective for weaning children from tube to oral feeding.
  • Amitriptyline is not a critical component of this successful feedingWeaning protocol.
Abstract

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