[Short-term antibiotic prophylaxis with ceftriaxone in general surgery]

Area of Science:

• Infectious Diseases
• Surgical Antibiotic Prophylaxis
• Pharmacology

Background:

• Surgical site infections (SSIs) are a significant concern in patient outcomes.
• Antimicrobial prophylaxis is crucial for preventing SSIs in elective surgery.
• Long-acting cephalosporins offer potential for effective, single-dose prophylaxis.

Purpose of the Study:

• To evaluate the efficacy of a single intravenous dose of ceftriaxone for short-term antimicrobial prophylaxis.
• To determine the success rate of ceftriaxone in preventing infections in surgical patients.

Main Methods:

• A study involving 100 patients undergoing elective surgery.
• Administration of a single intravenous dose of ceftriaxone (1g or 2g) one hour prior to surgery.
• Assessment of therapeutic success in preventing post-operative infections.

Main Results:

• Therapeutic success was achieved in 92 out of 100 patients (92%).
• The single-dose regimen of ceftriaxone demonstrated high efficacy.
• Ceftriaxone proved effective as a short-term prophylactic agent.

Conclusions:

• Single-dose intravenous ceftriaxone is an effective antimicrobial prophylaxis for surgical patients.
• This regimen offers a successful strategy for reducing infection risk in elective procedures.
• Ceftriaxone is a viable option for short-term antibiotic prophylaxis in surgery.