Early-childhood BMI trajectories: evidence from a prospective, nationally representative British cohort study

B Stuart1, L Panico2

  • 1Senior Research Fellow, Primary Care and Population Sciences, Faculty of Medicine, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton, UK.

Nutrition & Diabetes
|March 8, 2016
PubMed

Insights

Childhood body mass index (BMI) trajectories are established early, with obesity linked to socio-economic factors and early life mechanisms like smoking during pregnancy. Early intervention is key to addressing childhood obesity and lifelong health outcomes.

Area of Science:

  • Pediatric obesity research
  • Developmental trajectories
  • Socio-economic determinants of health

Background:

  • Childhood overweight and obesity rates are rising, particularly in the UK, with 20% of children affected by age 5.
  • Socio-economic inequalities significantly influence childhood and adult obesity.
  • Early childhood is a critical period for establishing lifelong body mass index (BMI) trajectories.

Purpose of the Study:

  • To identify distinct latent trajectories of body mass index (BMI) from ages 3 to 11 years in British children.
  • To examine the socio-economic characteristics and underlying mechanisms during pregnancy and infancy associated with these BMI trajectories.
  • To understand the early-life origins of childhood obesity and overweight.

Main Methods:

  • Utilized a nationally representative prospective cohort study of 9,699 UK children born between 2000-2002.
  • Collected interviewer-measured height and weight data at ages 3, 5, 7, and 11 years.
  • Employed latent growth mixture models to calculate BMI trajectories and multinomial models to analyze socio-economic factors.

Main Results:

  • Identified four BMI trajectories: normal weight (85%), overweight (14.4%), and obese (3.1%).
  • The obese trajectory was distinct by age 3, while the overweight trajectory diverged around age 5.
  • Significant socio-economic inequalities were observed, with early mechanisms like pregnancy smoking and not breastfeeding mediating disadvantage for the obese group.

Conclusions:

  • Childhood BMI trajectories, particularly for obesity, are established very early in life.
  • Strong socio-economic patterns suggest early life roots for growing health inequalities.
  • Pregnancy and infancy mechanisms are crucial for the obese trajectory; further research on age 5 mechanisms is needed for the overweight trajectory.
Abstract

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