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An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
Prevention of primary liver cancer by immunization
1Royal Free Hospital School of Medicine, London, U.K.
Abstract:
Primary liver cancer is one of the ten most common cancers of man and approximately 80% of cases are associated etiologically with infection with hepatitis B virus (HBV), often early in life. Infection with HBV is now preventable by active immunization, so that large-scale immunization programs will prevent the initial infection and the development of persistent infection and the carrier state, the most important risk factor in hepatocarcinogenesis.
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