Related Experiment Video
Updated: Mar 24, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
Impact of Alcohol on Outcomes in Hospitalized Major Trauma Patients: A Literature Review
Elizabeth Anne Leonard1, Tom Buckley, Kate Curtis
1Sydney Nursing School (Ms Leonard, Dr Buckley, and Dr Curtis), University of Sydney, Sydney, New South Wales, Australia; Department of Trauma (Ms Leonard), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia; and Department of Trauma (Dr Curtis), South Eastern Sydney Local Heath District, Sydney, New South Wales, Australia.
Abstract:
To critically appraise available studies investigating the impact of alcohol outcomes in hospitalized patients after major trauma. Outcomes included injury severity, mortality, complications, and hospital/intensive care length of stay. Data were sourced from MEDLINE, CINAHL, and SCOPUS databases. Abstracts were screened for inclusion/exclusion criteria with 15 articles appraised and analyzed based on in-hospital outcomes. Although alcohol intoxication is associated with a marginal increase in the incidence of in-hospital complications (sepsis and multiorgan failure), overall studies suggest it is not associated with longer intensive care or in-hospital length of stay. This literature review also demonstrated decreased mortality and injury severity in patients with traumatic brain injury. Further research is required to determine the reasons for these associations.
Related Concept Videos
Hypothesis Test for Test of Independence
H0: The two variables (factors)...
CNS Depressants: Alcohol and Nicotine
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:

