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Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
Health resource utilization varies by comorbidities in children with epilepsy
Klajdi Puka1, Mary Lou Smith2, Rahim Moineddin3
1Department of Psychology, Hospital for Sick Children, Toronto, ON, Canada.
Insights
Children with epilepsy and comorbidities like depression, anxiety, and learning disabilities experience higher healthcare use. Identifying and managing these conditions is crucial to reduce costly emergency department visits and hospitalizations.
Area of Science:
- Pediatric Neurology
- Health Services Research
- Epidemiology
Background:
- Comorbidities in adults with epilepsy are linked to increased health resource utilization (HRU).
- The association between comorbidities and HRU in pediatric epilepsy populations is not well-established.
- Understanding this relationship is vital for optimizing healthcare resource allocation in children with epilepsy.
Purpose of the Study:
- To investigate the association between comorbidities and health resource utilization (HRU) in children with epilepsy.
- To determine if mental health and developmental comorbidities increase healthcare utilization in pediatric epilepsy patients.
- To identify specific comorbidities that significantly impact neurology visits, emergency department (ED) visits, and hospitalizations.
Main Methods:
- Utilized health administrative databases from Ontario, Canada.
- Evaluated the frequency of neurologist visits, ED visits, and hospitalizations.
- Assessed the impact of comorbidities (depression, anxiety, learning disability, ADHD, ASD) on HRU, adjusting for demographic and socioeconomic factors.
Main Results:
- Comorbid depression, autistic spectrum disorder (ASD), and learning disability increased neurology visits.
- All evaluated comorbidities significantly increased ED visits.
- Comorbid depression, anxiety, ASD, and learning disability were associated with increased hospitalizations.
- Learning disability demonstrated the most substantial impact on overall HRU.
- Each additional comorbidity increased the frequency of neurology visits, ED visits, and hospitalizations significantly.
Conclusions:
- Mental health and developmental comorbidities are associated with increased HRU in children with epilepsy.
- Different comorbidities uniquely influence specific types of HRU.
- Early identification and management of these comorbidities are essential to mitigate the risk of costly healthcare utilization, including ED visits and hospitalizations.
Objectives:
Comorbidities in adults with epilepsy have been shown to significantly increase health resource utilization (HRU). The current study aimed to determine whether a similar association exists among children with epilepsy in a universal health insurance system.
Methods:
Health administrative databases in Ontario, Canada were used to evaluate the frequency of neurologist visits, emergency department (ED) visits, and hospitalizations. We evaluated the association between HRU and comorbidities, including depression, anxiety, learning disability, attention deficit hyperactivity disorder (ADHD), and autistic spectrum disorder (ASD), adjusting for age, sex, residence, and socio-economic status.
Results:
The frequency of neurology visits was increased by comorbid depression, ASD, and learning disability (adjusted relative risk [aRR]=1.29-2.07; p<.01). The frequency of ED visits was increased by all comorbidities (aRR=1.26-2.83; p<.0001). The frequency of hospitalizations was increased by comorbid depression, anxiety, ASD, and learning disability (aRR=1.77-7.20; p<.0001). Learning disability had the largest impact on HRU. For each additional comorbidity, the frequency of neurology visits, ED visits, and hospitalizations increased by 1.64 to 3.16 times (p<.0001).
Conclusions:
Among children with epilepsy, mental health and developmental comorbidities were associated with increased HRU, and different comorbidities influenced different types of HRU. In addition, we highlight the importance of identifying and managing these comorbidities, as they increased the risks of costly HRU such as ED visits and hospitalizations.
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