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Bacteremia and Deep Vein Thrombosis in an Infant
Louis G Pruitt1, Joel C Mosley1, Richard F Lasseigne1
1Department of Emergency Medicine, Louisiana State University Health Sciences Center, Baton Rouge, Louisiana; Our Lady of the Lake Children's Hospital, Baton Rouge, Louisiana.
Insights
Deep vein thrombosis (DVT) is rare in infants, but leg swelling can signal this serious condition. Early diagnosis via ultrasound and prompt treatment are crucial for infants with DVT.
Area of Science:
- Pediatric Medicine
- Emergency Medicine
- Vascular Medicine
Background:
- Deep vein thrombosis (DVT) is uncommon in infants but frequently observed in hospitalized children, often linked to central venous catheters.
- In pediatric cases, DVT signifies a hypercoagulable state, necessitating swift diagnosis and management of both the clot and its root cause.
Observation:
- A previously healthy 6-month-old male presented with unilateral leg swelling, a symptom leading to emergency department evaluation.
- Duplex ultrasonography identified multiple deep vein thromboses (DVTs) in the affected leg's vasculature.
- Blood cultures confirmed methicillin-resistant Staphylococcus aureus (MRSA) infection, indicating a potential underlying cause for the thrombosis.
Findings:
- New-onset extremity swelling in infants can be an initial presentation of deep vein thrombosis (DVT).
- Duplex ultrasonography is a valuable, non-invasive tool for emergency physicians to diagnose or exclude DVT in infants.
- The presence of DVT in pediatric patients may indicate critical underlying conditions such as infection or malignancy.
Implications:
- Emergency physicians must consider DVT in infants presenting with limb swelling, even if rare.
- Prompt diagnosis and management of DVT in children are essential for preventing complications and addressing associated critical illnesses.
- This case highlights the importance of considering DVT in the differential diagnosis of infant leg swelling, especially when associated with infection like MRSA.
Background:
Deep vein thrombosis (DVT) is rare in infancy. In pediatric populations, thrombosis occurs most frequently in hospitalized children and those with central venous catheters. The presence of a DVT in the general pediatric population indicates a hypercoagulable state and requires rapid diagnosis and treatment of both the thrombosis and the underlying process.
Case Report:
A previously healthy 6-month-old male was brought to the emergency department by his family with a chief complaint of left leg swelling. Duplex ultrasonography in the emergency department revealed multiple DVTs in the leg vasculature. The patient was treated with anticoagulation and antibiotic therapy in the emergency department and admitted. Blood cultures revealed the subsequent growth of methicillin-resistant Staphylococcus aureus (MRSA). WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: While rare in infants, new-onset swelling in an extremity may be caused by thrombosis and be the initial symptom of an underlying hypercoagulable state. Duplex ultrasonography is a relatively benign test that can be readily performed in most emergency departments, and it allows physicians to rule out thrombosis. When present, DVT in the general pediatric population can indicate a critical illness, such as malignancy or infection, and requires rapid treatment and admission to a pediatric service for management.
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