Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study

MikoŁaj P Zaborowski1, Leonora Balaj1, Xandra O Breakefield1

  • 1Mikołaj P. Zaborowski ( mzaborowski@mgh.harvard.edu ; mikolaj.zaborowski@gmail.com ), Leonora Balaj ( balaj.leonora@mgh.harvard.edu ), Xandra O. Breakefield ( breakefield@hms.harvard.edu ), and Charles P. Lai ( drcplai@gmail.com ) are affiliated with the Department of Neurology at Massachusetts General Hospital, in Charlestown, and with the Harvard NeuroDiscovery Center at Harvard Medical School, in Boston, Massachusetts. XOB is also affiliated with the Department of Radiology at Massachusetts General Hospital, in Charlestown, and MPZ is also affiliated with the Department of Gynecology, Obstetrics, and Gynecologic Oncology at the Poznan University of Medical Sciences, in Poland.

Bioscience
|March 9, 2016
PubMed
Summary

Extracellular vesicles (EVs), including exosomes and microvesicles, are crucial for cell communication and cargo transfer. This review covers EV composition, uptake, biological effects, and advanced study methods.

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