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Multiple Giant Pilar Cyst Distributed Over the Body Since Childhood

Ali Asilian1, Amir Hossein Siadat2, Zabiolah Shahmoradi1

  • 1Department of Pathology, Isfahan University of Medical Science Isfahan, Isfahan, Iran.

Indian Journal of Dermatology
|March 9, 2016
PubMed

Insights

Multiple giant pilar cysts, which are keratin-filled growths, can occur throughout the body. In rare cases, these cysts can transform into squamous cell carcinoma (SCC), a type of skin cancer.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Trichilemmal cysts, also known as pilar cysts, are benign growths originating from the external root sheath of hair follicles.
  • These cysts typically contain keratin and its byproducts and are commonly found on the scalp.

Purpose of the Study:

  • To report a rare case of multiple giant pilar cysts distributed widely over the body.
  • To highlight the potential malignant transformation of a pilar cyst into squamous cell carcinoma (SCC).

Main Methods:

  • Case report presentation.
  • Clinical examination and histopathological analysis of the cyst and the malignant transformation.

Main Results:

  • A 55-year-old male presented with numerous large pilar cysts since childhood, affecting the entire body.
  • One of the giant pilar cysts on the chest had transformed into squamous cell carcinoma.

Conclusions:

  • Multiple giant pilar cysts are a rare clinical presentation.
  • Pilar cysts have the potential to undergo malignant transformation into squamous cell carcinoma, necessitating careful monitoring and management.

Keywords:
Bodypilar cystsquamous cell carcinoma

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