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Related Experiment Video

Updated: Mar 24, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Multiple Cutaneous Reticulohistiocytoma.

Karishma D Hemmady1, Shylaja S Someshwar1, Hemangi R Jerajani1

  • 1Department of Dermatology, Mahatma Gandhi Mission Hospital, Navi Mumbai, Maharashtra, India.

Indian Journal of Dermatology
|March 9, 2016
PubMed
Summary
This summary is machine-generated.

Multicentric reticulohistiocytosis, a rare histiocytosis, typically involves arthritis and systemic issues. This case highlights multiple cutaneous lesions as the sole manifestation, emphasizing the need for thorough investigation.

Keywords:
Ground glass cytoplasmmulticentric reticulohistiocytosismultiple cutaneous reticulohistiocytosis

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Area of Science:

  • Dermatology
  • Rheumatology
  • Pathology

Background:

  • Multicentric reticulohistiocytosis (MRH) is a rare non-Langerhans cell histiocytosis.
  • It classically presents with destructive arthritis, skin nodules, and systemic involvement.
  • Cutaneous lesions can appear before, during, or after other symptoms.

Purpose of the Study:

  • To report a unique case of MRH presenting solely with multiple cutaneous lesions.
  • To emphasize the importance of comprehensive evaluation in diagnosing MRH.
  • To contribute to the understanding of MRH's diverse clinical spectrum.

Main Methods:

  • Case report of a patient with multiple cutaneous reticulohistiocytomas.
  • Thorough clinical, radiological, and laboratory investigations were performed.
  • Histopathological examination confirmed the diagnosis.

Main Results:

  • The patient presented with multiple cutaneous reticulohistiocytomas.
  • Extensive investigations revealed no evidence of systemic disease or arthritis.
  • Histopathology confirmed reticulohistiocytoma without systemic associations.

Conclusions:

  • This case demonstrates an unusual presentation of MRH.
  • Cutaneous lesions can be the only manifestation of MRH.
  • Thorough investigation is crucial to rule out systemic involvement in suspected MRH cases.