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Updated: Mar 24, 2026

Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
Published on: April 5, 2024
Effect of aerobic exercise during pregnancy on antenatal depression
Mervat M El-Rafie1, Ghada M Khafagy2, Marwa G Gamal3
1Department of Public Health, Cairo University, Giza, Egypt.
Background:
Antenatal depression is not uncommon and is associated with a greater risk of negative pregnancy outcomes.
Aim:
Exploring the effect of exercise in preventing and treating antenatal depression.
Methods:
This was a prospective interventional controlled study carried out in 100 pregnant women treated at the Ain-Shams Family Medicine Center and Maadi Outpatient Clinic, Cairo, Egypt. The participants were divided into two groups (n=50 in the exercise group and n=50 in the control group). The exercise group regularly attended supervised sessions for 12 weeks. The activities in each session included walking, aerobic exercise, stretching, and relaxation. The control group completed their usual antenatal care. The Center for Epidemiological Studies Depression Scale (CES-D) was used to assess depression symptoms at the first interview and immediately after the 12-week intervention.
Results:
Compared to the control group, the exercise group showed significantly improved depressive symptoms as measured with the CES-D after the 12-week intervention on the CES-D (P=0.001). Within groups, the exercise group demonstrated a significant improvement of depressive symptoms from baseline to intervention completion, while the control group demonstrated no significant changes over time.
Conclusion:
Exercise during pregnancy was positively associated with reduced depressive symptoms.
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