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Cutaneous collagenous vasculopathy: A rare case report.

Kinjal Deepak Rambhia1, Snehal D Hadawale2, Uday S Khopkar1

  • 1Department of Dermatology, Seth GS Medical College, KEM Hospital, Mumbai, Maharashtra, India.

Indian Dermatology Online Journal
|March 9, 2016
PubMed
Summary

Cutaneous collagenous vasculopathy (CCV) is a rare condition often misdiagnosed. Histology reveals unique vessel wall changes, aiding in its accurate diagnosis and differentiation from similar dermatoses.

Keywords:
Cutaneous collagenous vasculopathydilated superficial dermal vesselshyalinemicroangiopathy

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Area of Science:

  • Dermatology
  • Vascular Biology
  • Histopathology

Background:

  • Cutaneous collagenous vasculopathy (CCV) is a rare and frequently underdiagnosed condition.
  • CCV presents clinically with nonblanchable macules, often on the lower extremities.
  • Differential diagnoses include pigmented purpuric dermatoses and cutaneous small vessel vasculitis.

Observation:

  • A case of CCV in a 50-year-old woman is presented.
  • Lesions were asymptomatic, erythematous to hyperpigmented macules on the lower extremities.
  • Histological examination showed dilated superficial dermal vessels with hyaline material in the vessel walls.

Findings:

  • Histology revealed characteristic findings of dilated superficial dermal vessels.
  • Abundant pink hyaline material within the vessel walls was observed.
  • Periodic acid Schiff (PAS) staining confirmed the presence of hyaline material, aiding CCV diagnosis.

Implications:

  • Accurate diagnosis of CCV is crucial for appropriate patient management.
  • Histopathological differentiation from pigmented purpuric dermatosis and generalized essential telangiectasia is emphasized.
  • Increased awareness can improve diagnosis rates for this underrecognized condition.