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Updated: Mar 24, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss

Published on: January 25, 2016

Endothelial dysfunction in patients with sudden sensorineural hearing loss.

Nezamoddin Berjis¹, Maryam Moeinimehr¹, Seyyed Mostafa Hashemi¹

¹Department of Otolaryngology, Isfahan University of Medical Sciences, Isfahan, Iran.

Advanced Biomedical Research

|March 9, 2016

Summary

Endothelial dysfunction is linked to sudden sensorineural hearing loss (SSNHL). This study found impaired flow-mediated dilation (FMD) in SSNHL patients, independent of other cardiovascular risks.

Keywords:

Brachial artery diameter endothelial dysfunction sudden sensorineural hearing loss

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Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage

Published on: February 10, 2023

Area of Science:

Cardiology
Otolaryngology
Vascular Biology

Background:

Endothelial dysfunction is a potential contributor to sudden sensorineural hearing loss (SSNHL).
Investigating the link between vascular health and hearing impairment is crucial.

Purpose of the Study:

To determine the relationship between endothelial dysfunction and SSNHL.
To assess if endothelial function is an independent risk factor for SSNHL.

Main Methods:

A case-control study involving 30 SSNHL patients and 30 healthy controls.
Assessed endothelial function using flow-mediated dilation (FMD) and collected demographic and laboratory data.
Evaluated cardiovascular risk factors including diabetes, dyslipidemia, and smoking history.

Main Results:

SSNHL patients exhibited significantly lower FMD compared to controls (6.21% vs. 11.52%, P < 0.001).
Diabetes and dyslipidemia were more prevalent in the SSNHL group.
Logistic regression confirmed FMD as an independent predictor of SSNHL (OR=0.439, P=0.002).

Conclusions:

Endothelial dysfunction is significantly associated with SSNHL.
This association persists independently of common cardiovascular risk factors like diabetes and dyslipidemia.