Bisphenol A exposure and children's behavior: A systematic review
Maede Ejaredar1,2, Yoonshin Lee1, Derek J Roberts1,3
1Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Journal of Exposure Science & Environmental Epidemiology
|March 10, 2016
Summary
Exposure to Bisphenol A (BPA), an endocrine disruptor, during pregnancy and childhood is linked to behavioral issues in children. This systematic review found associations with anxiety, depression, hyperactivity, and conduct problems.
Area of Science:
- Environmental Health
- Developmental Psychology
- Toxicology
Background:
- Bisphenol A (BPA) is an endocrine-disrupting chemical widely used in plastics and resins.
- Previous studies suggest a potential link between BPA exposure and altered children's behavior.
Purpose of the Study:
- To systematically review existing literature on the association between prenatal and childhood BPA exposure and behavioral outcomes in children up to 12 years of age.
Main Methods:
- Searched multiple electronic databases (MEDLINE, PubMed, EMBASE, PsycINFO, CINAHL, ERIC) and conference abstracts.
- Included original studies measuring BPA metabolites in urine and children's behavioral outcomes.
- Analyzed 11 articles from 2811 initial citations.
Main Results:
- Prenatal BPA exposure was associated with increased anxiety, depression, aggression, and hyperactivity in children.
- Childhood BPA exposure linked to higher levels of anxiety, depression, hyperactivity, inattention, and conduct problems.
- Limited evidence suggests BPA exposure is associated with adverse behavioral outcomes.
Conclusions:
- Observational evidence indicates a link between prenatal and childhood BPA exposure and adverse behavioral outcomes.
- Further prospective cohort studies are necessary to confirm these associations and understand causality.
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