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Stress Hyperglycemia During Surgery and Anesthesia: Pathogenesis and Clinical Implications
Nadine E Palermo1, Roma Y Gianchandani2, Marie E McDonnell3
1Department of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School, 221 Longwood Ave, Suite 381, Boston, MA, 02115, USA. npalermo@bwh.harvard.edu.
Perioperative hyperglycemia, often transient stress hyperglycemia (SH), is linked to poor outcomes. Understanding SH
Area of Science:
- Medical research
- Clinical outcomes
- Endocrinology
Background:
- Perioperative hyperglycemia is associated with adverse clinical outcomes.
- Many hospitalized patients experience transient stress hyperglycemia (SH) without prior diabetes history.
Purpose of the Study:
- To discuss the epidemiology and pathogenesis of SH.
- To review evidence on predisposing factors and outcomes of SH.
- To highlight the need for further research on SH sequelae and management.
Main Methods:
- Literature review on stress hyperglycemia.
- Analysis of epidemiological data.
- Synthesis of evidence on predisposing factors and outcomes.
Main Results:
- Stress hyperglycemia (SH) is a common phenomenon in hospitalized patients.
- SH is linked to negative clinical outcomes.
- Predisposing factors and specific outcomes require further investigation.
Conclusions:
- Further research is essential to understand long-term SH effects.
- Investigating perioperative glucose modulation and optimal treatment strategies is crucial.
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