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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Related Experiment Video

Updated: Mar 24, 2026

Working with Human Tissues for Translational Cancer Research
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NCCN Work Group Report: Emerging Issues in Tissue Allocation.

Jessica K DeMartino

    Journal of the National Comprehensive Cancer Network : JNCCN
    |March 10, 2016
    PubMed
    Summary

    Access to high-quality human tissue specimens is crucial for molecular profiling research. Proper acquisition, handling, and patient consent are essential for scientifically accurate translational studies.

    Area of Science:

    • Translational research
    • Biomedical research
    • Molecular profiling

    Background:

    • Increasing demand for molecular profiling in academia and industry.
    • Growing challenges in tissue allocation for clinical and translational research.
    • Need for high-quality biospecimens for scientific accuracy.

    Purpose of the Study:

    • To address the growing issue of tissue allocation in research.
    • To emphasize the importance of high-quality biospecimens.
    • To highlight the role of patients and best practices in biospecimen management.

    Main Methods:

    • Review of current practices in tissue acquisition and handling.
    • Analysis of stakeholder needs in clinical research.
    • Emphasis on patient consent and custodianship.

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    Main Results:

    • Tissue allocation is a significant challenge for researchers.
    • High-quality biospecimens are critical for reliable study outcomes.
    • Patients are active partners in the research process.

    Conclusions:

    • Human tissue specimens are valuable resources requiring careful management.
    • Adherence to best practices for acquisition, handling, and consent is paramount.
    • Collaboration among all stakeholders ensures the integrity of biospecimen use.