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Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

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Inflammatory Myofibroblastic Tumor: A Case Study.

Christopher L Powell¹, Jeffrey M Holzbeierlein¹, Louis Wetzel²

¹Department of Urology, University of Kansas Medical Center, Kansas City, KS, USA.

Urology Case Reports

|March 10, 2016

Summary

Inflammatory myofibroblastic tumor (IMT) is a rare benign bladder lesion. High suspicion is needed as IMT mimics malignant tumors, requiring surgical removal for diagnosis.

Keywords:

Fibromyxoid tumor Inflammatory tumor Pseudotumor

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Area of Science:

Uropathology
Oncology
Surgical Pathology

Background:

Inflammatory myofibroblastic tumor (IMT) is a rare benign neoplasm.
IMT can occur in various body sites, including the genitourinary tract.
Distinguishing IMT from malignant bladder tumors preoperatively is challenging.

Observation:

A 21-year-old woman presented with acute, painful, obstructive, and irritative voiding symptoms.
Preoperative evaluations did not yield a definitive diagnosis.
The patient underwent a partial cystectomy for the bladder lesion.

Findings:

Final histopathological examination confirmed the diagnosis of inflammatory myofibroblastic tumor (IMT).
The lesion was a solid mass that mimicked malignancy on imaging and endoscopic evaluation.

Implications:

A high index of clinical suspicion is crucial for diagnosing IMT.
Early and accurate diagnosis of IMT is essential to differentiate it from malignant bladder neoplasms.
Surgical intervention may be necessary for definitive diagnosis and treatment of IMT.