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Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Related Experiment Video

Updated: Mar 24, 2026

Teratoma Generation in the Testis Capsule

Teratoma Generation in the Testis Capsule

Published on: November 7, 2011

Oral teratoma.

Shreesh S Kolekar¹, Tejas Chincholi¹, Nitin Nangare¹

¹Department of Surgery, Krishna Institute of Medical Sciences, Karad, Maharastra, India.

International Journal of Applied & Basic Medical Research

|March 10, 2016

Summary

Congenital teratomas in the oropharyngeal cavity are rare, often presenting with respiratory distress in newborns. This case highlights successful surgical management of a palatal teratoma in a neonate.

Area of Science:

Pediatric Surgery
Neonatal Medicine
Developmental Biology

Background:

Congenital teratomas are rare germ cell tumors.
Oropharyngeal teratomas represent a very small percentage of all teratomas.
Prenatal diagnosis of oropharyngeal teratomas is infrequent.

Observation:

A female neonate presented with respiratory distress.
The neonate had a teratoma located in the palate.
This rare condition required immediate medical and surgical intervention.

Findings:

The palatal teratoma was successfully diagnosed and surgically removed.
The neonate's airway was secured, enabling further management.
Complete surgical excision led to a positive outcome.

Keywords:

Cleft palate oropharyngeal cavity teratoma

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Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

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Last Updated: Mar 24, 2026

Teratoma Generation in the Testis Capsule

Teratoma Generation in the Testis Capsule

Published on: November 7, 2011

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation

Fate Mapping of Human Embryonic Stem Cells by Teratoma Formation

Published on: August 1, 2010

Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

Targeted and Selective Treatment of Pluripotent Stem Cell-derived Teratomas Using External Beam Radiation in a Small-animal Model

Published on: February 17, 2019

Implications:

Early recognition and airway management are critical for neonates with oropharyngeal teratomas.
Surgical intervention is the primary treatment modality for these tumors.
This case underscores the importance of prompt pediatric intervention for rare neonatal conditions.