Related Experiment Video
Updated: Mar 24, 2026

03:26
Detrusor Underactivity Model in Rats by Conus Medullaris Transection
Published on: August 28, 2020
2.4K
Sacral Nerve Stimulation for Neurogenic Bladder.
Lai-Fung Li1, Gilberto Ka-Kit Leung1, Wai-Man Lui1
1Division of Neurosurgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
World Neurosurgery
|March 11, 2016
Summary
Neurogenic bladder, caused by nervous system diseases, leads to urinary dysfunction. Sacral nerve stimulation offers a feasible treatment strategy by restoring neural function.
Area of Science:
- Urology
- Neurology
- Biomedical Engineering
Background:
- Neurogenic bladder is urinary dysfunction from nervous system diseases, impacting urine storage and voiding.
- Common causes include multiple sclerosis and spinal cord injury, leading to UTIs, retention, and potential renal failure.
- Effective treatment is crucial to prevent severe health consequences and improve life expectancy.
Purpose of the Study:
- To review the pathophysiology of neurogenic bladder.
- To discuss sacral nerve stimulation as a therapeutic strategy.
- To compare the Brindley procedure and sacral neuromodulation.
Main Methods:
- Literature review of neurogenic bladder pathophysiology.
- Analysis of sacral nerve stimulation techniques.
- Comparison of the Brindley procedure and sacral neuromodulation.
Main Results:
- Neurogenic bladder results from neurological damage affecting bladder control.
- Sacral nerve stimulation aims to restore neural function for bladder control.
- The Brindley procedure and sacral neuromodulation are key SNS methods.
Conclusions:
- Neurogenic bladder requires effective management to prevent renal complications.
- Sacral nerve stimulation presents a viable therapeutic option.
- Understanding SNS methods is key for clinical application.
Related Concept Videos
The Micturition Reflex
3.5K
Urination, or micturition involves the coordination of the bladder's detrusor muscle and two sphincters to ensure controlled bladder emptying.
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
The process begins with bladder filling, where the bladder wall stretches as urine accumulates. This stretching activates the urine storage reflex, mediated by the sacral spinal segments and the pontine storage center. Efferent sympathetic impulses stimulate the detrusor muscle to relax and the internal urethral sphincter to contract, facilitating...
3.5K
Urinary Bladder
4.2K
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
4.2K

