Clinical Characteristics and Urodynamic Analysis of Urinary Dysfunction in Multiple Sclerosis

Area of Science:

• Neurology
• Urology

Background:

• Lower urinary tract dysfunction and symptoms are prevalent in multiple sclerosis (MS) patients.
• The real prevalence and therapeutic effects of urinary symptoms in MS require further investigation.

Purpose of the Study:

• To analyze major urinary symptoms and urodynamic abnormalities in MS patients.
• To observe the therapeutic effects of treatments based on different MS characteristics.

Main Methods:

• 126 MS patients with urological dysfunction were assessed using the Overactive Bladder System Score (OABSS), urodynamic investigation, and Expanded Disability Status Scale (EDSS).
• Changes in urinary symptoms and urodynamic parameters were monitored post-treatment.

Main Results:

• Urgency was the predominant symptom, and detrusor overactivity was the major bladder dysfunction.
• Positive correlation found between EDSS and OABSS.
• Clinically isolated syndrome (CIS), relapsing-remitting MS, and progressive MS showed significant improvements in various urinary symptom and urodynamic parameters after treatment.

Conclusions:

• Urodynamic parameters are crucial for accurate diagnosis and management of MS-related urinary dysfunction.
• Early and effective treatment can enhance bladder function and quality of life in early-stage MS.